Publicaties en Nieuws

Publicaties van de lectoraatsleden van het lectoraat Analysetechnieken in de Life Sciences

1. Synthesis vs. salvage of ester- and ether-linked phosphatidylethanolamine in the intracellular protozoan pathogen Toxoplasma gondii.
Ren B, Liang X, Brouwers JF, Miron RC, Shen B, Gupta N.

  • Commun Biol. 2023 Mar 22;6(1):306. doi: 10.1038/s42003-023-04664-x.
  • PMID: 36949328 Free PMC article.

2. Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis.
Hendriks D, Brouwers JF, Hamer K, Geurts MH, Luciana L, Massalini S, López-Iglesias C, Peters PJ, Rodríguez-Colman MJ, Chuva de Sousa Lopes S, Artegiani B, Clevers H.

  • Nat Biotechnol. 2023 Feb 23. doi: 10.1038/s41587-023-01680-4. Online ahead of print.
  • PMID: 36823355

3. Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids.
Renne MF, Bao X, Hokken MW, Bierhuizen AS, Hermansson M, Sprenger RR, Ewing TA, Ma X, Cox RC, Brouwers JF, De Smet CH, Ejsing CS, de Kroon AI.

  • EMBO J. 2022 Dec 17;41(2):e106837. doi: 10.15252/embj.2020106837. Epub 2021 Dec 7.
  • PMID: 34873731 Free PMC article.

4. PMAP-36 reduces the innate immune response induced by Bordetella bronchiseptica-derived outer membrane vesicles.
Balhuizen MD, Versluis CM, van Harten RM, de Jonge EF, Brouwers JF, van de Lest CHA, Veldhuizen EJA, Tommassen J, Haagsman HP.

  • Curr Res Microb Sci. 2020 Sep 25;2:100010. doi: 10.1016/j.crmicr.2020.100010. eCollection 2021 Dec.
  • PMID: 34841304 Free PMC article.

5. Genetic analysis of plasmid-encoded mcr-1 resistance in Enterobacteriaceae derived from poultry meat in the Netherlands.
Jamin C, Sanders BK, Zhou M, Costessi A, Duijsings D, Kluytmans JAJW, van Alphen LB, Schrauwen EJA.

  • JAC Antimicrob Resist. 2021 Nov 11;3(4):dlab156. doi: 10.1093/jacamr/dlab156. eCollection 2021 Dec.
  • PMID: 34806003 Free PMC article.

6. Lipidome of cricket species used as food.
Tzompa-Sosa DA, Dewettinck K, Provijn P, Brouwers JF, de Meulenaer B, Oonincx DGAB.

  • Food Chem. 2021 Jul 1;349:129077. doi: 10.1016/j.foodchem.2021.129077. Epub 2021 Jan 19.
  • PMID: 33571921

7. Control of n-Butanol Induced Lipidome Adaptations in E. coli.
Jeucken A, Zhou M, Wösten MMSM, Brouwers JF.

  • Metabolites. 2021 Apr 29;11(5):286. doi: 10.3390/metabo11050286.
  • PMID: 33947169 Free PMC article.

8. Kinetics of Physiological Responses as a Measure of Intensity and Hydration Status During Experimental Physical Stress in Human Volunteers.
Kartaram SW, van Norren K, Schoen E, Teunis M, Mensink M, Verschuren M, M'Rabet L, Besseling-van der Vaart I, Mohrmann K, Wittink H, Garssen J, Witkamp R, Pieters R.

  • Front Physiol. 2020 Sep 4;11:1006. doi: 10.3389/fphys.2020.01006. eCollection 2020.
  • PMID: 33013439 Free PMC article.

9. Prevalence and abundance of selected genes conferring macrolide resistance genes in COPD patients during maintenance treatment with azithromycin.
Djamin RS, Talman S, Schrauwen EJA, von Wintersdorff CJH, Wolffs PF, Savelkoul PHM, Uzun S, Kerstens R, van der Eerden MM, Kluytmans JAJW.

  • Antimicrob Resist Infect Control. 2020 Jul 28;9(1):116. doi: 10.1186/s13756-020-00783-w.
  • PMID: 32723393 Free PMC article. Clinical Trial.

10. Lipid Analysis of the 6-Hydroxydopamine-Treated SH-SY5Y Cell Model for Parkinson's Disease.
Xicoy H, Brouwers JF, Kalnytska O, Wieringa B, Martens GJM.

  • Mol Neurobiol. 2020 Feb;57(2):848-859. doi: 10.1007/s12035-019-01733-3. Epub 2019 Sep 6.
  • PMID: 31493240 Free PMC article.

11. Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System.
Siegers JY, van de Bildt MWG, Lin Z, Leijten LM, Lavrijssen RAM, Bestebroer T, Spronken MIJ, De Zeeuw CI, Gao Z, Schrauwen EJA, Kuiken T, van Riel D.

  • J Virol. 2019 May 15;93(11):e02273-18. doi: 10.1128/JVI.02273-18. Print 2019 Jun 1.
  • PMID: 30867311 Free PMC article.

12. A Comprehensive Functional Characterization of Escherichia coli Lipid Genes.
Jeucken A, Molenaar MR, van de Lest CHA, Jansen JWA, Helms JB, Brouwers JF.

  • Cell Rep. 2019 Apr 30;27(5):1597-1606.e2. doi: 10.1016/j.celrep.2019.04.018.
  • PMID: 31042483

13. The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses.
Linster M, Schrauwen EJA, van der Vliet S, Burke DF, Lexmond P, Bestebroer TM, Smith DJ, Herfst S, Koel BF, Fouchier RAM.

  • J Virol. 2019 Apr 3;93(8):e01907-18. doi: 10.1128/JVI.01907-18. Print 2019 Apr 15.
  • PMID: 30700609 Free PMC article.